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zestril 20 mg tablet Previous estimates are that around five in 100,000 people have PSP, but Coyle-Gilchrist wants to put a figure on?a person's lifetime risk of getting it. Research has much wider potential as well, he says, because it could unlock other neurological conditions. Unlike most forms of dementia: "When we see?someone with typical PSP, we?can be very confident of what is happening in their brains; the buildup of an abnormal protein called tau. That same protein plays a role in Parkinson's and?Alzheimer's. So we have a unique opportunity to study how tau affects our brain and how we can try to stop it."